In July 2004, after graduating, Li Yiman joined the Nanjing Yue Opera Troupe to specialize in Yin style young actors. During the filming of the new version of "Dream of the Red Chamber", she also won the championship of the "Yuyao Cup" National Youth Yue Opera Competition.

In 2008, Li Yiman officially entered the film and television industry by starring in director Li Shaohong's "Dream of the Red Chamber".

In 2010, Li Yiman starred in the family romance drama "Cannot Have No Mother" directed by Huang Jingwei; In the same year, Li Yiman also starred in the movie "Home Beyond the Frontier".

In 2012, Li Yiman starred in the emotional and ethical drama "Watchful Sky".

In 2013, Li Yiman starred in the modern legendary drama "The Legend of the Condor Heroes".

In January 2014, the TV drama "The Legend of the Condor Heroes" starring Li Yiman officially premiered; In the same year, Li Yiman also starred in the fashion romance inspirational drama "The Billion Heirs".

In June 2015, Li Yiman starred in the war themed TV drama "Memories of the Same Clan".

In 2016, Li Yiman participated in the performance of the suspense drama "Hunter".

In March 2021, Li Yiman participated in the romantic drama "Song Dynasty Palace Poetry" and played Xu Shangfu in the play.

On January 23, 2024, Li Yiman took on the role of screenwriter for the TV drama "The Return of War", which was successfully broadcasted on CCTV-6 channel.