In 2018, Zhai Zilu starred in his first TV drama "Full time Master", officially entering the entertainment industry; In the same year, she starred in the urban romance drama "The World Owes Me a First Love".

In 2019, won the Annual Potential TV Drama Actor Award at the Tencent Video Starlight Awards.

In 2020, co starred with Liu Shishi and Zhu Yilong in the urban emotional drama "Dear Myself".

In January 2021, the youth campus drama "Hello, Opposing Debater 2" was broadcasted as the lead actor; In August of the same year, the campus youth drama "Quick witted First Half" starring was broadcasted; With the broadcast of two works, Zhai Zilu, as the protagonist, has attracted more attention.

In March 2022, released her first single "Expired"; In the same year, the leading roles in the ancient costume drama "Years of Reclining" and the youth drama "My Calorie Boy" were successively broadcasted; In December, he was selected for the Star Ocean Young Actor Selection Program for his urban drama "A Year Without Jobs".

On May 4, 2023, Zhai Zilu participated in the 30th College Student Film Festival Youth Night; On December 29th, the costume romance drama "Strangers Like Jade" starring the lead actor was broadcasted.

On September 9, 2024, the TV drama "Youthfulness in the Wind" with the lead actor was broadcasted; On September 10th, the TV drama "When the Mountain Flowers Are Blooming" featuring specially invited lead actors was broadcasted.

On January 14, 2025, the TV drama "Jinnang Miaolu" starring will be broadcasted; On March 3rd, she starred in the TV drama "Northbound" and played the role of Shao Xingchi; The comedy film "Adventure" in which I will participate is scheduled for August 8, 2025.